High sodium painkillers, vitamin supplements, and other common drugs in soluble form may be bad for your heart, found a new study. Researchers found that effervescent, dispersible, and soluble prescription drugs were associated with an increased risk of cardiovascular events, in an analysis of prescription data on 1, 292, 337 UK patients.

The median consumption  of sodium from soluble drugs was 106, 8 mmol/day, higher than the recommended daily sodium take of 104 mmol/day in the UK. Researchers found that 61, 071 people had cardiovascular event, such as heart attack, stroke, or cardiovascular-related death, during the follow-up of 7, 2 years. So, Should You Eat Salt? In comparison to those who took standard formulations of meds, those with prescribed soluble forms had a 16% higher risk of having a cardiovascular event. The use of soluble drugs was also associated with a 22% higher risk of non-fatal stroke, a 7-times higher risk of high blood pressure, and a 28% higher risk of all-cause mortality.

Lead author Jacob George from the University of Dundee says that doctors ought to be aware of the risks of using soluble meds and prescribe them only when benefits outweigh risks. These could include various over-the-counter (OTC) meds, aspirin, effervescent vitamin supplements or Alka Seltzer, say the authors of the study. Those using soluble drugs or soluble OTC meds should be warned about its potential dangers due to the high sodium content,  says George. Try these 5 New Rules for a Healthy Heart.